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Phase III trial for Sutent halted

Big Pharm scores a victory against cancer

Earlier this year, Redstate lost Mark Kilmer to cancer.  Our community is not alone–cancer touches almost all of us either directly or through one that we love.  And while treatments have certainly been progressing, the battle seems an uphill one.

Today, however, there is some good news.

“Big Pharm” poster child Pfizer announced it is halting the phase three trial of its new pancreatic drug Sutent.  Generally you might think that’s bad news–that the drug causes some hideous unforeseen side effect.  But no, in this case it is because Sutent is so effective that the FDA has taken the rare step of hurrying the drug to market to help those currently suffering from the disease.

I don’t claim to be an expert on the development of pharmaceuticals, but it seems to me that Stutent is a good example of the sort of creative innovation that can take place in the drug industry (among others, come to think of it) when it is incentivized to bring new products to market.  Maybe these companies should do long, expensive and potentially risky reseach out of the goodness of their hearts–certainly those who have eagerly demonized the big drug companies seem to think this is the preferred model–but the fact is that they are more likely to do it if they are going to make a profit. 

There has been a disturbing lack of new products in the pharmaceutical research and development pipeline recently.  Maybe that’s just serendipity, but maybe it reveals the dampening effect the threat of socialized medicine has had on the industry.  Why make the investment if you can’t market your invention? 

For the moment, however, Pfizer is up 7% in pre-market trading.  Good for them and good for us.

COMMENTS

  • Praying

    and we have the goons in Washington deciding who, if anyone, should be able to get these new, effective, but expensive drugs. I am thrilled to hear of this success – just more reason why we need to be VERY CAREFUL about rushing into a state of socialized medicine. And with this administration, it’s all about rushing into things.

  • Swamp_Yankee

    Its such hard cancer to detect and its impossible to cure. May father and my uncles dies of pancreatic cancer and it certainly does not get enough attention.

  • Brian Hibbert

    I have a family member who just underwent massive surgery for this cancer. Even with the surgery and chemotherapy, his doctors give him odds at < 50% for survival.

    This is a really nasty cancer so ANY hope is great news!

    Thanks for keeping us up to date on this AE.

    • barry915barry
    • Husker

      My Uncle is going through the same thing right now. However, it had advanced to his bones before it was caught. The prognosis is pretty dim for him, but maybe others can benefit from this breakthrough.

  • MORepublican

    My grandmother passed away last August from pancreatic cancer, and this type of cancer is insidious. She found out in May, so it was less than three months. She was a healthy 88 year-old (probably could have lived several more years were it not for the cancer), and I didn’t even recognize her at the end, she became so frail and ghostly.

    At least we had some time with her before she passed. I hope this drug can help prevent other families from what we went through. Maybe this can help Patrick Swayze as well (I think he has pancreatic cancer) and bring more attention to this type of cancer.
    Pancreatic cancer does not get the attention it should. It has one of the highest death rates, if not highest, of all cancers, and it needs more attention.

  • Take_Your_Meds

    And it’s already available for treating other cancers.

    Depending on dosage Sutent costs as much as $300 PER PILL.

    A four week course for treating gastrointestinal stromal tumor, for example, will cost more than $30,000.00. If Pfizer follows the same course that has been followed for other drugs that get approved for additional diseases, it is possible they will charge even more for the drug when it is prescribed for pancreatic cancer. (There is no way to know now if that will be the case, but it has happened in the past.)

    A drug is only useful if you can afford it.

    • Darin_H

      A drug is only useful if you can afford it.

      Also, a drug is only useful if it’s developed.

      Also, a drug is only useful when a company who develops it can stay in business to create it.

      Did you know prices come down? Even without government interference….

    • Take_Your_Meds

      I got distracted. If the pill is $300, then a month (28 pills) is over $8000. I’m not sure how long the drug therapy lasts.

  • Academic Elephant

    And I have corrected.

    As to your other point, is it better not to have the drug than to have it be expensive? Do you think it would have been developed if it weren’t profitable?

    • Take_Your_Meds

      What I wrote isn’t refuted by anything you have, can, or could write (except of course my math error).

      If a drug is unaffordable is has no utility to someone who is dying — especially in the case of a disease like pancreatic cancer that usually has such a poor prognosis.

      I have no problem with drug companies making a profit (a substantial profit), but I am well aware of all the cases of drug company behavior, including abusive pricing, that has involved illegal, unethical, and in some cases immoral behavior. Immorality is problematic, because it isn’t necessarily illegal; it speaks to character, not criminal culpability.

  • Vladimir